5 A Toolkit for Healthcare Professionals Calculating Your Disease Risk: A Look Into the PREVENT Calculator WEBINAR/TUTORIAL: Introducing the American Heart Association PREVENT™ Equations To estimate CVD risk comprehensively and accurately for people without existing CVD, the American Heart Association developed the Predicting Risk of Cardiovascular Disease EVENTs (PREVENT™) equations. Deployed in 2023, the PREVENT equations are the newest, most comprehensive risk estimation tool and the first to combine cardiovascular, kidney and metabolic health measurements to support primary prevention-focused treatment decisions. It’s important for clinicians to utilize the PREVENT equations in routine clinical practice for the primary prevention of cardiovascular disease. What Are the PREVENT Equations? The PREVENT equations are an updated approach to cardiovascular risk assessment, building on the Pooled Cohort Equations (PCE), also known as the ASCVD calculator. They were derived and validated using data from more than 6.5 million U.S. adults across multiple datasets and validated for adults aged 30 to 79 years without known CVD. Compared with prior tools, the PREVENT equations incorporate contemporary, diverse data and expanded clinical inputs, including kidney and metabolic measures. This broader approach supports more comprehensive risk assessment and better informed decisions regarding medications, lifestyle changes, and follow-up care to improve CKM health and reduce both short- and long-term CVD risk. The PREVENT equations estimate 10- and 30-year absolute risk for total CVD, atherosclerotic CVD (ASCVD), and HF. They also use lower thresholds for CVD risk, which may help identify individuals who could benefit from preventive therapies earlier.7 Target Population: The PREVENT equations are validated specifically for U.S. adults aged 30 to 79 years without established CVD, with all required clinical input values. PREVENT equations estimate 10- and 30-year absolute risk for: PREVENT-CVD (total cardiovascular disease: ASCVD + HF) PREVENT-ASCVD (atherosclerotic cardiovascular disease) PREVENT-HF (heart failure) The PREVENT calculator can also provide a “PREVENT Age” based on the 10-year PREVENT-CVD risk estimate and a risk percentile based on the 30-year PREVENT-CVD risk estimate. Accessing the PREVENT equations with the American Heart Association PREVENT™ online calculator can help inform discussions and shared decision-making with patients about cardiovascular disease risk and provide opportunities for primary CVD prevention and care optimization over the life course.3,4,5,6 PREVENT™ Online Calculator Understanding Risk Assessment: Introducing the PREVENT equations WEBINAR/TUTORIAL: Development and Validation of the American Heart Association’s PREVENT Equations AHA SCIENTIFIC STATEMENT:
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