13 #AHA24 ScientificSessions.org Christopher Barnett, MD, MPH, associate chief for inpatient services, Division of Cardiology and chief of the Critical Care Cardiology section at University of California, San Francisco Health, said the registry can help U.S. cardiology specialists complement the work being done in Europe. “The evidence being generated for how to take care of these patients is coming from both sides of the Atlantic and around the world,” Barnett said. “We’re both looking for the best evidence to understand how best to treat patients. We have similar goals in mind, but we’re approaching that using the unique characteristics of tools that we have in the U.S.” An important difference between the U.S. and Europe regarding research is differing regulatory structures, allowing things to progress along different paths, Alviar said. “Their regulatory processes have allowed our European colleagues to develop robust research at a different pace, particularly randomized control trials, in conditions that are more challenging to execute in the United States,” he said. Alastair Proudfoot, MBChB, FRCP (Edin), FFICM, PhD, a consultant in critical care and lead for cardiogenic shock at Barts Heart Centre in London, highlighted potential advantages of the collaboration. “Rather than being competing entities, trans-Atlantic collaborations should leverage such differences in research priorities, structure and ethics to complement each other,” he said. “For example, established U.S. registry infrastructure should inform the focus of future clinical trials in Europe, where the deferred consent model may lend itself to clinical trial enrollment in adults lacking capacity. Similarly, the development of collaborative trans-Atlantic biobanks will support mechanistic insights into cardiac critical care and opportunities for validation of novel findings across jurisdictions.” Regardless of the differences, Barnett said the U.S. and Europe are reaching some of the same conclusions regarding acute cardiac care. “Despite the fact that we have very different systems … many different people from many different parts of the world are arriving at the same space. I don’t think that’s coincidence,” he said. “Everyone’s taking different pathways, but we are all arriving at the same place.” TRANS-ATLANTIC continued from page 7 Watch AHAtv, your source for Science News and Scientific Sessions highlights. Check the #AHA24 home page for bonus video and streaming content throughout the meeting. Supported by:
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